Damage to the nervous tissue of the central nervous system (brain-spinal cord) with objective neurological indication of intractable spasticity, and other associated neuropathies.
Dyskinetic and spastic movement disorders.
HIV / AIDS.
Inflammatory bowel disease.
Opioid use disorder for which conventional therapeutic interventions are contraindicated or ineffective, or for which adjunctive therapy is indicated in combination with primary therapeutic interventions.
Post-traumatic stress disorder.
Severe chronic or intractable pain of neuropathic origin or severe chronic or intractable pain.